BrainsCAN Fellows
BrainsCAN is bringing the world’s most promising early career cognitive neuroscientists to Western University through the Postdoctoral Fellowship Program. Training the next generation of researchers is a key aim of BrainsCAN, and its fellows are the engines of innovative research.
In fall 2017, the first set of fellows joined the program under the designation of a BrainsCAN Fellow or Postdoctoral Associate.
Learn about the BrainsCAN Fellows and their research.
Current BrainsCAN Fellows:
Olamide Adebiyi, Marta De Felice, Sarah Hayes, Chenxi He, Priya Kalra, Cassandra Lowe, Emily Nichols, Ana Luísa Pinho, Nichole Scheerer, Ashley Schormans, Kasey Van Hedger
Former BrainsCAN Fellows:
Craig Allen, Justine Cléry, Björn Herrmann, Kaitlin Laidlaw, Pan Liu, Liya Ma, Jie Mei, Daniel Miller, Aline Miranda, Mina Nashed, Amy Reichelt, David Schaeffer, Mojtaba Soltanlou, Stephen Van Hedger, Eric Wilkey, Jeff Weiler, Yiming Xiao

BrainsCAN Fellow
PhD, Veterinary Physiology – University of Ibadan, Ibadan, Nigeria
Harnessing optogenetics to treat demyelination and cognitive impairment in multiple sclerosis
Supervisor(s): Dr. Tim Bussey, Dr. Ravi MenonMultiple sclerosis (MS) leads to devastating impairments in cognitive functions due to loss of myelin and associated disruption of nerve conduction. Presently, existing treatments for MS are ineffective in treating the accompanying cognitive dysfunctions. Thus, effective treatment of this debilitating demyelinating disease represents an urgent unmet need. Recent findings indicate that remyelination can be stimulated by artificially-driven neuronal activity. Particularly promising is optogenetic stimulation (OS); a precise way to manipulate neurons with light by genetic introduction of light-sensitive proteins. Given that cognitive impairments are a major issue in MS, it would be of considerable interest if this strategy could be successfully applied to enhance cognition. Hippocampal glutamatergic neurons (HGNs) are excitatory neurons essential for learning, memory and attention. The disruptions in their numbers and density have been implicated in the pathogenesis of MS.My focus is to target HGNs via OS with the aim of improving cognition and promoting remyelination in MS. Our findings may be used to guide procedures using extant techniques such as MRI-informed deep brain stimulation of regions which could potentially accomplish the same cognitive rescue in a less target specific stimulation approach.

BrainsCAN Fellow
PhD in Neuroscience - University of Cagliari (Italy)
Investigating the neurodevelopmental aberrations on hippocampal formation induced by adolescent THC exposure
Supervisor(s): Dr. Steve Laviolette, Dr. Walter Rushlow, Dr. Shawn WhiteheadResearch Information:
The recent legalization of cannabis for both medicinal and recreational purposes has altered the perception of risks, resulting in a sustained increase of cannabis use mainly among adolescents. This trend is concerning given that sustained consumption of marijuana during such vulnerable neurodevelopmental window has been associated with a wide range of long-lasting cognitive impairments and enhanced risks for neuropsychiatric diseases, such as schizophrenia, anxiety and mood disorders. In addition, emerging evidence has pointed out critical sex-related differences in neuropathological outcomes induced by marijuana consumption. In this study, the impairments in cognitive and affective processing will be investigated in a translational rodent model of adolescent cannabis exposure. Using a multi-level approach, cognitive performances, anxiety and psychiatric-like manifestations will be evaluated, concomitant with a detailed examination of molecular biomarkers and neural activity in selected brain regions relevant for cognition and neuropsychiatric disorders. The findings obtained by the proposed research will enhance our knowledge on the neurobiological mechanisms underlying the side effects of cannabis exposure on the adolescent brains in both genders and will aid in developing novel potential pharmacotherapeutic strategies to reverse the cannabis-related pathology.
BrainsCAN Fellow
PhD, Neuroscience and AuD, Audiology - University at Buffalo
Neuroinflammatory Regulation of Noise-Induced Auditory and Cognitive Impairment
Supervisor(s): Dr. Brian Allman, Dr. Shawn Whitehead, Dr. Wataru InoueResearch Information:
Hearing loss is one of the most prevalent chronic health conditions, affecting more than 1.2 billion people worldwide. It is well-recognized that excessive exposure to loud noise, resulting from environmental (e.g., city noise), recreational (e.g., loud music) and occupational (e.g., industry workers) insults, is a leading cause of permanent hearing loss. Beyond the devastating effects of hearing impairment itself, there is clear evidence that loud noise exposure also leads to pathology in brain regions both within and beyond the auditory pathway. For example, noise exposure can cause aberrant auditory perceptions such as tinnitus (i.e., “ringing in the ears”), as well as cognitive impairments in learning and memory tasks that do not depend on the auditory system. While the neural mechanisms contributing to noise-induced tinnitus and cognitive impairment remain elusive, accumulating evidence suggests that neuroinflammation plays an important role in mediating the brain plasticity thought to underlie these disorders. Using a combination of cell-specific in vivo neuroimaging and auditory/cognitive behavioural testing, my research aims to reveal how noise-induced neuroinflammation leads to aberrant neural activity in areas of the brain that control auditory perception, learning, memory and other higher-order cognitive functions. Ultimately, this work will address our crucial need to better understand the adverse effects of noise exposure on brain health.

BrainsCAN Fellow
PhD, Philosophy - Beijing Normal University, Beijing, China
The impact of pediatric hearing loss on mathematics and underlying neural reorganizations
Supervisor(s): Dr. Daniel Ansari, Dr. Blake ButlerResearch Information:
Sensory loss has significant perceptual, social, and economic impacts. Deaf children often experience challenges in receiving appropriate learning accommodations. Among these difficulties, mathematics learning is an important issue, as school-entry numerical skills are a more important predictor of subsequent academic achievement than early reading and socio-emotional skills. That hearing impairment might exacerbate mathematics difficulties (which are present at a rate comparable to reading difficulty in normally developed children) also warrants considerable concern. However, little is known about how deafness impacts brain processes beyond the domain of low-level perception. Thus, my research seeks to investigate how sensory impairment affects higher-level cognitive functions associated with mathematics, in order to gather evidence potentially informing remediation strategies in this population. My work aims: 1) to determine whether behavioral differences exist between hearing and deaf individuals on mathematical tasks that engage different components of working memory, 2) to characterize differences in the neural correlates of these tasks between groups, and 3) to compare developmental trajectories of behavioral and neural measures between groups by examining both children and adults.

BrainsCAN Fellow
EdD, Human Development and Education - Harvard Graduate School of Education
The role of the medial temporal lobe in implicit learning: mechanisms and representations
Supervisor(s): Dr. Paul Minda, Dr. Laura Batterink, Dr. Marc JoanisseImplicit learning—that is, learning without effort or awareness of what has been learned—plays an important role in many domains, including first language acquisition. There is increasing evidence that developing expertise or fluency in these domains involves not only the accumulation of information, but changes in the way that information is represented. For example, experts emphasize relevant features over irrelevant features and often use higher-order representations of the stimuli (such as “chunks”). However, the computational and neural mechanisms of these representational changes are not well understood. I will use a combination of behavioral, computational, and neuroimaging techniques to characterize these shifts. Understanding these changes in representation is critical to designing more effective methods of instruction and training.

PhD, Public Health and Health Systems - University of Waterloo
Determining the neural circuits underlying excessive food intake in adolescents and young adults
Supervisor(s): Dr. J. Bruce Morton, Dr. Lindsay BodellThe sustained and excessive consumption of calorie-dense foods is the leading cause of preventable chronic disease and premature death worldwide. Limiting the consumption of these foods is therefore essential to maintain optimal health. However, in the modern food-rich environment, maintaining a healthy diet has become a difficult endeavor. The environment is saturated with unhealthy ultra-processed calorie-dense foods (those high in saturated fats and sugar), and these foods are often cheaper than their healthier counterparts. This is coupled with omnipresent cues, in the form of media advertisements, to consume these foods. While some individuals find it really difficult to control calorie-dense food consumption in this environment, others are more adept. My research seeks to understand why some individuals are more prone to overconsumption than others. Specifically, my body of research seeks to understand the neural circuits underlying vulnerability to over consumption, with the particular focus on how the prefrontal cortex regulates reward circuits in the brain to modulate consumptive behaviours across developmental contexts. By delineating these neurobiological processes, we will be able to identify the subtle cognitive and neural markers that increase the propensity to overeat. This would enable researchers and clinicians to identify those individuals that may be more likely to respond to a given intervention and provide the foundational work necessary to develop novel evidence-based interventions.
Publications:
Trends in Cognitive Sciences: Review suggests a reciprocal relationship between obesity and self-control
The Lancet: Adolescents prone to poor dietary choices, leading to changes in the brain

PhD, Medical Sciences - McMaster University
Examining the effects of prenatal THC exposure on prefrontal-hippocampal interactions and long-term cognitive development
Supervisor(s): Dr. Steven Laviolette, Dr. Daniel Hardy, Dr. Walter RushlowUp to 20% of pregnant women self-report using cannabis during pregnancy. With recent decriminalization and progressive legalization of recreational cannabis in North America, this figure is projected to increase. While the THC component of cannabis has been shown to impair fetal growth in clinical populations and animal models, our understanding of the developmental effects, and associated neural pathways, of maternal cannabis consumption is currently lacking. This project will address this knowledge gap in a model of prenatal cannabis exposure. Specifically, the effects of cannabis constituents on cognition (e.g. learning and memory) will be investigated at the levels of behaviour, neural pathways, and brain structures. The goal of this project is to improve postnatal developmental outcomes and inform public awareness of the risks associated with prenatal cannabis consumption.

BrainsCAN Fellow
PhD, Psychology - Western University
Functional connectivity in fetal growth restriction: association with delivery times and long-term language outcomes
Supervisor(s): Dr. Emma Duerden, Dr. Sandrine de RibaupierreResearch Information:
Intrauterine growth restriction (IUGR) is a serious condition where the placenta stops growing late in pregnancy, limiting oxygen to the fetal brain. In the early stages of IUGR, blood flow is still being directed to the frontal lobes. Later, however, blood is directed to midbrain areas important for keeping the fetus alive. This redistribution referred to as ‘brain sparing’. Brain sparing can result in severe brain injury, with adverse consequences for cognitive function, including language. For these fetuses, early delivery can prevent death; however premature birth also comes at a cost. The neonatal ICU is a stressful environment, and preterm babies are at risk of both short- and long-term health issues. Objective measures to guide decisions regarding delivery time to maximize developmental outcomes are crucial to neonatal care in this population. My research aims to evaluate whether brain sparing is associated with decreased functional and structural connectivity in the language network in utero, and if connectivity measures are associated with language outcomes at 12- and 24-months. By using MRI-based methods to monitor fetuses at risk for IUGR, and following the developmental trajectory of the newborns, I aim to improve newborn brain health and cognitive outcomes, specifically later language development.

PhD, Biomedical Sciences - University of Coimbra, Coimbra, Portugal and Karolinska Institutet, Stockholm, Sweden
Novel brain atlasing techniques to reveal cerebellar role in music cognition
Supervisor(s): Dr. Joern Diedrichsen, Dr. Jessica GrahnResearch Information:
Understanding the role of the cerebellum in human cognition asks for the functional mapping of its territories upon performance of a wide array of behavioral tasks. To this end, functional Magnetic Resonance Imaging (fMRI) has been used to measure brain activation related to specific behaviors as means to extensively characterize functional responses in the cerebellar circuitry. The overlap of the neural substrates across tasks can elucidate us about the contribution of the cerebellum to brain processes directly linked to elementary mental functions. Herein, we will adopt this cognitive-atlasing approach to investigate the interplay of the cortico-cerebellar circuits in the domain of music cognition. We will generate a large-scale task-fMRI dataset comprising both the Multi-Domain Task Battery—which covers a broad range of cognitive modules—and a new set of musical tasks dedicated to specifically assessing different music abilities. This resource will allow us to determine the common basis and relationship between music and general cognition as well as obtain a systematic picture of the involvement of cerebellar regions in these neurocognitive mechanisms. Moreover, the dataset will be made publicly available in dedicated neuroimaging repositories, in order to become the groundwork for the development of cognitive brain-atlasing infrastructures targeting the human cerebellum.

BrainsCAN Fellow
PhD, Philosophy – Wilfrid Laurier University
The impact of sensory-motor control of speech on social communication and development in children with and without Autism Spectrum Disorders across the lifespan
Supervisor(s): Dr. Ryan Stevenson, Dr. Janis Cardy, Dr. David PurcellSpeech is arguably the most important form of human communication. Since the goal of speech production is the transfer of information, speech production must be carefully regulated to ensure the desired information is conveyed. During speech production sensory feedback, such as auditory feedback, plays an important role in maintaining the fluidity of speech, as it allows speech motor movements to be monitored and production errors to be detected and corrected. A major focus of my research program is investigating how the role of sensory feedback in the control of speech changes throughout development in individuals with and without autism spectrum disorder. I am also interested in how the ability to extract and utilize the information contained in sensory feedback influences the development of higher-order cognitive processes such as speech communication, emotion regulation, and social competence.

BrainsCAN Fellow
PhD, Neurobiology and Neurosciences, Western University
The Neural Basis of Audiovisual Temporal Perception: From Cortical Networks to Cellular Mechanisms
Supervisor(s): Dr. Brian Allman, Dr. Wataru InoueResearch Information:
To form a coherent perception of the world around us, we are constantly processing and integrating sensory information from multiple modalities. In fact, when auditory and visual stimuli occur within ~100 ms of each other, individuals tend to perceive the stimuli as a single event, even though they occurred at separately. Although this integration of closely-timed audiovisual stimuli can offer certain behavioral advantages, an overly broad window of temporal integration can be problematic (e.g., in autism and schizophrenia), as information from truly separate events may not be perceived correctly. While recent studies in humans have suggested that the binding of audiovisual stimuli is regulated by neural oscillations, the brain circuits and cellular mechanisms that regulate the putative oscillatory activity subserving audiovisual perceptual binding remains unknown. Using our translational behavioural task in combination with optogenetics and in vivo electrophysiology, my research aims to uncover the mechanisms by which inhibitory neurotransmission finely controls audiovisual perception. Ultimately, these studies will significantly advance our understanding of the neuronal circuitry underlying audiovisual temporal perception, and will be the first to establish the role of interneurons in regulating the synchronized neural activity that is thought to contribute to the precise binding of audiovisual stimuli.

PhD, Psychology - University of Chicago
Examining striatal-mediated cognitive function in patients with substance use and obsessive-compulsive disorders
Supervisor(s): Dr. Penny MacDonald, Dr. Ali Khan, Dr. Adrian OwenSubstance use disorder (SUD) and obsessive compulsive disorder (OCD) are common psychiatric illnesses categorized by abnormal thoughts (i.e., cravings or obsessions) that motivate habitual behaviors and can cause distress and dysfunction. Prior studies have found that patients with SUD and OCD have abnormalities in brain regions involved in learning and reward processing (e.g., the striatum), specifically those that rely on the neurotransmitter dopamine. Notably, these same regions are heavily affected in Parkinson’s disease (PD), either because of the disease itself or because of the treatment. Our research takes a novel approach to studying SUD and OCD by using techniques that have been developed in studies of PD patients and healthy controls, like structural and functional MRI and pharmacological manipulations of dopamine. The goal of this project is to uncover the neural basis for symptoms that are shared across striatum-involved disorders by using similar methods and comparing results from patients with SUD, OCD, and PD. This approach has the potential to inform more effective treatments.
Former BrainsCAN Fellows

Assistant Professor
McGill University
BrainsCAN Postdoctoral Associate (2017 - 2021)
BrainsCAN Fellow (2021 - 2022)
Ultra-high field functional mapping of the multisensory integration network in NHPs
Supervisor(s): Dr. Stefan Everling, Dr. Ravi Menon, Dr. Stefan Everling, Dr. Andrew Pruszynski
PhD, Neurosciences and Cognition - Université Claude Bernard Lyon I, France

Assistant Professor
Rotman Research Institute (Baycrest)
University of Toronto
BrainsCAN Fellow (2018 - 2020)
PhD, Psychology - University of Leipzig, Germany

Financial Institution/Industry
BrainsCAN Fellow (2018 - 2019)
Uncovering the neural representations of the intentions that drive action, and the role of intentional action in social settings
Supervisor(s): Jody Culham, Mel Goodale
PhD, Psychology (Cognitive Science) - University of British Columbia

Assistant Professor
North Dakota State University
The effect of attention bias training on adolescent internalizing problems: Neurobehavioral predictors and mechanism
Supervisor(s): Dr. Elizabeth Hayden, Dr. Marc Joanisse
PhD, Communication Sciences & Disorders - McGill University

Assistant Professor
Federal University of Minas Gerais Brazil
Targeting the epichaperome to improve cognitive deficits in mouse models of synucleinopathies
Supervisor(s): Dr. Marco Prado, Dr. Vania Prado
PhD, Neuroscience and Neuroinflammation - Cleveland Clinic, Lerner Research Institute

Senior Medical Writer
INVIVO Communications
Examining the effects of prenatal THC exposure on prefrontal-hippocampal interactions and long-term cognitive development
Supervisor(s): Dr. Steven Laviolette, Dr. Daniel Hardy, Dr. Walter Rushlow
PhD, Medical Sciences - McMaster University

University of Adelaide
BrainsCAN Fellow (2019 - 2020)
Defining nutritional influences on neural network structure and function across development
Supervisor(s): Dr. Lisa Saksida, Dr. Ravi Menon
PhD, Behavioural Neuroscience - Cardiff University

Assistant Professor
University of Surrey
How do we know 'two' but not 'three' means '●●' objects? Neural correlates of symbolic number knowledge in preschoolers
Supervisor(s): Dr. Daniel Ansari, Dr. Marc Joanisse
PhD, Neuroscience – University of Tübingen